Antidepressants and chronic pain, targeting chlorine makes the difference

Antidepressants and chronic pain, targeting chlorine makes the difference

Chronic neuropathic pain is associated with nerve damage that affects 8% of the population in France. With the exception of antiepileptics and so-called tricyclic antidepressants (TCA) or serotonin and norepinephrine reuptake inhibitors (SNRIs) which have very partial efficacy, there is no effective treatment without serious side effects. Among the targets of antidepressants, serotonin neurons are …

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